Lip deseases, Diseases of the lips, Diseases of the lips Trauma, Fissures, Leukoplakia Thehealthtime.com Diseases of the lips. The vermilion of the lips was conceptualized by Jean Darier as the semi-mucosa. The anatomy of the lips is transitional from skin to mucous membrane. This article emphasizes inflammatory diseases of the lips known as cheilitis. Angular cheilitis is a reactive process with several possible causes, including infections, mechanical, nutritional...